Chronic myelogenous leukemia: a concise update
نویسندگان
چکیده
منابع مشابه
Chronic myelogenous leukemia: a concise update.
HRONIC MYELOGENOUS leukemia (CML) is a C clonal myeloproliferative disorder of the primitive hematopoietic stem cell.’-3 It involves the myeloid, erythroid, megakaryocytic, B-, and sometimes T-lymphoid elements, but not the marrow fibrobla~ts.~,~ CML is characterized by (1) the heterogeneity of the disease among patients, (2) a biphasic or triphasic course, and (3) the presence of a chromosomal...
متن کاملChronic myelogenous leukemia: update on biology and treatment.
Chronic myelogenous leukemia (CML) is a myeloproliferative disorder that follows a characteristic clinical course in which a chronic phase of variable duration precedes an accelerated, and ultimately blastic, phase, which is generally fatal. This disorder results from a clonal expansion of transformed hematopoietic progenitor cells and includes myeloid, monocytic, erythroid, megakaryocytic, and...
متن کاملChronic Myelogenous Leukemia: Update on Biology and Treatment
The M. D. Anderson group is responsible for the first observation, has been instrumental in dissecting the cells responsible for the graft-vs-leukemia (GVL) effect noted in the second, and has been among the leaders in devising novel technologies to detect the chromosomal abnormalities mentioned in the third. It is therefore only natural that members of this group should provide a timely update...
متن کاملChronic Myelogenous Leukemia: Update on Biology and Treatment
The M. D. Anderson group is responsible for the first observation, has been instrumental in dissecting the cells responsible for the graft-vs-leukemia (GVL) effect noted in the second, and has been among the leaders in devising novel technologies to detect the chromosomal abnormalities mentioned in the third. It is therefore only natural that members of this group should provide a timely update...
متن کاملFlow Cytometry in Chronic Myelogenous Leukemia Blast Crisis
Background: Chronic myelogenous leukemia (CML) is a myeloproliferative disorder due to BCR-ABL1 translocation. Patients showing transformation into blast crisis (BC) have poorer treatment response and prognosis. Methods: A retrospective study was conducted in the department of Pathology, Maulana Azad Medical College, New Delhi, India, over a time period of 5 years (2014-2019) to evaluate the ...
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ژورنال
عنوان ژورنال: Blood
سال: 1993
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v82.3.691.691